P94Fetal cerebrovascular response to chronic hypoxia
نویسندگان
چکیده
منابع مشابه
Chronic hypoxia alters fetal cerebrovascular responses to endothelin-1.
In utero hypoxia influences the structure and function of most fetal arteries, including those of the developing cerebral circulation. Whereas the signals that initiate this hypoxic remodeling remain uncertain, these appear to be distinct from the mechanisms that maintain the remodeled vascular state. The present study explores the hypothesis that chronic hypoxia elicits sustained changes in fe...
متن کاملFetal cerebrovascular response to chronic hypoxia--implications for the prevention of brain damage.
Fetal hypoxia is one of the leading causes of perinatal morbidity and mortality. One of the most severe sequels of fetal hypoxic insult is the development of perinatal brain lesions resulting in a spectrum of neurological disabilities, from minor cerebral disorders to cerebral palsy. One of the most important fetal adaptive responses to hypoxia is redistribution of blood flow towards the fetal ...
متن کاملCerebrovascular response to hypoxia in young vs aged rats.
Cerebrovascular responses of young and aged rats were tested to graded levels of hypoxia using a modification of the Levine ischemic-hypoxic rat model in which one carotid artery was ligated. Rats were anesthetized with 70% N2O, 30% O2 and cortical and subcortical cerebral blood flow (CBF) were measured with radioactive microspheres. CBF and cerebral cortical oxygen consumption (CMRO2) were mea...
متن کاملHuman cerebrovascular response to combined hypoxia and hypercapnia.
The N2O technique was used in 6 human subjects to measure cerebral blood flow and metabolism during hypoxia and hypercapnia induced by the inhalation of 10% O2-5% CO2. Ventilation increased from 7.7 to 46.3 liters/min; Pao2 decreased from 88 to 62 mm Hg; Pacoo increased from 38 to 45 mm Hg (for each P < . 0 1 ) . Mean cerebral blood flow increased from 56 to 97 ml/100 g/min ( P < .01). Because ...
متن کاملPulmonary vascular response of the coati to chronic hypoxia.
The unusually muscular pulmonary arteries normally present in cattle and swine residing at low altitude are associated with a rapid development of severe pulmonary hypertension when those animals are moved to high altitude. Because these species lack collateral ventilation, they appear to have an increased dependence on hypoxic vasoconstriction to maintain normal ventilation-perfusion balance, ...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics and Gynecology
سال: 2000
ISSN: 0960-7692
DOI: 10.1046/j.1469-0705.2000.00004-1-93.x